Etoposide shortage — IT supply status & alternatives

Etoposide

ATC L01CB01

🇦🇺 AUST R 10233 · Link Medical Products Pty Ltd T/A Link Pharmaceuticals

In supply · Australia

Etoposido TevaEtoposido AccordETOPOPHOS etoposide

In supply · 🇦🇺 Australia · short in🇮🇹 IT

In supply in Australia

Reading today’s signals…

🇦🇺 AUAEMPA$193.50details →

✓ Can I substitute?

In supply

no shortage substitution needed

⇄ Best alternative

None listed

refer to prescriber

◷ Expected back

No estimate

No estimate provided

Product attributes reference data we hold

Active ingredient (INN)	Etoposide
Brand names	Etoposido Teva, Etoposido Accord, ETOPOPHOS etoposide
ATC level 5	L01CB01
ATC level 4	L01CB
Therapeutic category	Auto-created by FDA Drug Enforcement — Full Recall Database scraper
Controlled substance	No
Marketing-authorisation holders	FRESENIUS KABI LIMITED, HIKMA FARMACEUTICA (PORTUGAL) SA, NEON HEALTHCARE LIMITED, HIKMA PHARMACEUTICALS USA INC. +4 more
Registrations on file	17
Patient information leaflet (PIL)	Not on file
Summary of product characteristics (SPC)	Not on file

Trade price 🇦🇺 PBS · July 2026

🇦🇺 AU

● Official price on file

Ex-manufacturer

A$193.50

AEMP

Dispensed (DPMQ)

—

incl. fees

Pack

etoposide 100 mg/5 mL injection, 5 x 5 mL vials

Source: PBSEffective July 2026 · AUD

Substitution pathways 🇦🇺 Australia · TGA

—

No substitution instrument in force

Dispense per normal rules, or refer to the prescriber. No active SSSI/S19A instrument detected for this medicine.

How long have past shortages lasted? from 1 resolved event

◷

~2 months

Historical pattern from resolved shortage records — not a prediction of this event.

Global API supply base 🇺🇸 FDA Drug Master Files · active Type II

6 API manufacturers

Manufacturers with an active Type II Drug Master File — i.e. cleared to supply this active ingredient into the US market. A proxy for how concentrated the global manufacturing base is.

Moderate concentration risk

Cipla LTDJiangsu Hengrui Pharmaceuticals CO LTDNippon Kayaku CO LTDTapi Nl BVSichuan Huiyu Pharmaceutical CO LTDShandong Anhong Pharmaceutical CO LTD

Manufacturing countries: India, China, Japan · Source: FDA List of Drug Master Files

FDA-approved products 🇺🇸 Drugs@FDA

Approved applications

Generic (ANDA)

Brand (NDA/BLA)

Feb 2011

Latest approval

Shortage status by regulator official notices

🇮🇹

Italy

AIFA · 1d ago

Critical

Recalls official enforcement reports

🇺🇸

Etoposide

Infusion Options, Inc. · June 2019

Class IIdetails ↗

Verified timeline regulator events

🇮🇹 30 June 2026

critical reported

🇮🇹 15 Apr 2026

Shortage resolved

🇮🇹 3 July 2025

critical reported

🇮🇹 27 Sept 2024

critical reported

🇮🇹 10 Mar 2020

Shortage resolved

Sources official regulators

🇮🇹

AIFA

verified 1d ago

verify ↗

Registration recordmarketing-authorisation holders

Registrations & marketing-authorisation holders17 registrations · 8 MA holders

Product	Strength	Form	Market	MA holder	Status
ETOPOSIDE 20 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION	20 MG	solution	🇬🇧 GB	FRESENIUS KABI LIMITED	Active
ETOPOSIDE 20MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION	20MG	solution	🇬🇧 GB	HIKMA FARMACEUTICA (PORTUGAL) SA	Active
ETOPOSIDE 100 MG CAPSULE, SOFT	100 MG	capsule	🇬🇧 GB	NEON HEALTHCARE LIMITED	Active
ETOPOSIDE 50 MG CAPSULE, SOFT	50 MG	capsule	🇬🇧 GB	NEON HEALTHCARE LIMITED	Active
Etoposide	20mg/mL	injection	🇺🇸 US	HIKMA PHARMACEUTICALS USA INC.	Active
VEPESID etoposide	50mg	—	🇦🇺 AU	Link Medical Products Pty Ltd T/A Link Pharmaceuticals	Active
VEPESID etoposide	100mg	—	🇦🇺 AU	Link Medical Products Pty Ltd T/A Link Pharmaceuticals	Active
ETOPOPHOS Etoposide Phosphate	113.6mg	—	🇦🇺 AU	Link Medical Products Pty Ltd T/A Link Pharmaceuticals	Active
ETOPOPHOS etoposide	500mg	—	🇦🇺 AU	Link Medical Products Pty Ltd T/A Link Pharmaceuticals	Active
ETOPOPHOS etoposide	1g	—	🇦🇺 AU	Link Medical Products Pty Ltd T/A Link Pharmaceuticals	Active
Ebewe	50mg	—	🇦🇺 AU	Sandoz Pty Ltd	Active
Ebewe	100mg	—	🇦🇺 AU	Sandoz Pty Ltd	Active
Ebewe	200mg	—	🇦🇺 AU	Sandoz Pty Ltd	Active
Ebewe	400mg	—	🇦🇺 AU	Sandoz Pty Ltd	Active
Ebewe	1000mg	—	🇦🇺 AU	Sandoz Pty Ltd	Active

+2 more registrations on file

Mederti Drug Report

Generated 4 July 2026 · Australia market · 1 regulatory source

For health-professional reference only. Mederti aggregates shortage and substitution information from official regulatory sources. It is not clinical advice and data may be incomplete or delayed. Confirm any substitution or supply decision against the primary regulator source, the prescriber, and current clinical references (e.g. AMH) before acting. Terms.