20 active shortage notices across 7 countries · 2 anticipated.
Last updated 17 Sept 2026 · sourced from official medicines regulators
| high |
| 3 |
| 3 Jun 2026 |
| 28 Feb 2027 |
| FAMHP |
| Australia | high | 2 | 6 Aug 2025 | 22 May 2026 | TGA |
| France | high | 2 | 28 Nov 2024 | — | ANSM |
| European Union | high | 1 | 8 Sept 2023 | — | EMA |
| United States | medium | 5 | 13 Mar 2023 | — | FDA, FDA MedWatch |
| India | medium | 1 | 1 Jul 2026 | — | CDSCO |
Clinically related options from Mederti's curated alternatives data. Always confirm suitability with a pharmacist or prescriber before substituting.
Yes. As of the latest regulator updates, Methotrexate has 20 active shortage notices across 7 countries (Canada, Belgium, Australia, France, European Union, United States and more). Status is refreshed daily from official regulatory sources.
Regulators attribute the current Methotrexate shortages to unexpected increases in demand, manufacturing problems, causes not stated by the regulator. The exact cause varies by country and product — each notice on this page links to the official source.
Regulator-estimated resolution dates currently range from 30 Jun 2023 to 28 Feb 2027, depending on country and product. These estimates come from the manufacturers via regulators and often change — check the per-country table above for the latest.
Mederti lists 6 clinically related alternatives for Methotrexate (see the alternatives section above). Alternatives require clinical judgement — always confirm suitability with a pharmacist or prescriber and your national guidance before substituting.
Every shortage notice on this page is scraped daily from an official national medicines regulator (such as the FDA, TGA, MHRA or EMA) and linked back to its source. Mederti aggregates 40+ regulators across 50+ countries and never publishes unsourced shortage claims.
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